Oxford Nanopore Technologies

Job Description

Oxford Nanopore Technologies is headquartered at the Oxford Science Park outside Oxford, UK, with satellite offices and commercial presence in many global locations across the US, APAC and Europe. Oxford Nanopore employs from multiple subject areas including nanopore science, molecular biology and applications, informatics, engineering, electronics, manufacturing and commercialisation. The management team, led by CEO Dr Gordon Sanghera, has a track record of delivering disruptive technologies to the market.

Oxford Nanopore’s sequencing platform is the only technology that offers real-time analysis (for rapid insights), in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieve short to ultra-long read lengths.

Our goal is to enable the analysis of any living thing, by anyone, anywhere. We offer real-time nanopore-based DNA/RNA sequencing technology: accessible, easy to use and fully scalable for any requirement!

We are looking for a highly motivated individual to join the Protein Purification Team as a Research Scientist with a primary responsibility to engineer, express and purify enzymes for our disruptive nanopore sequencing technology.

The details…

Proteins form some of the most critical components of our technology. We continuously strive to improve and upgrade those components within our current sequencing technologies as well as develop novel functionalities to expand our disruptive platform. Working within a highly multi-disciplinary development team this primarily lab-based role will be focused on the expression, purification and characterisation of multiple protein types ranging from enzymatic motors to membrane nanopores.

You will be working alongside other scientists within the team and across the R&D department to deliver highly purified and characterised proteins for a variety of functions. This includes following established purification protocols as well as trouble-shooting and developing novel methodologies for all aspects of purification and testing.

What we’re looking for…

  • A BSc/MSc in a relevant scientific discipline (biochemistry, chemistry or related subject)
  • One to two years experience purifying proteins in industry or a post-qualification lab setting
  • A good working knowledge of recombinant protein expression, purification and subsequent characterisation
  • Hands on experience in working with AKTA systems and ability to troubleshoot expression and purification issues
  • Hands on experience in classical biochemical/biophysical protein characterisation techniques.
  • A knowledge of interrogating protein structure in silico for the design of mutant candidates would be beneficial

We are looking for applicants who can adapt quickly to new challenges and enjoy working with an agile approach to research!

You’ll be used to working meticulously and to a high standard, as well as being able to perform well under pressure. You’ll be used to meeting deadlines in a complex and fast paced environment.

Working within a dynamic, multidisciplinary team, successful candidates will be able to communicate results to other team members successfully.

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.

If you are looking to utilise your skills to really make a difference to humankind, then consider joining our team and apply today!

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, colour, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Please note that no terminology in this advert is intended to discriminate on the grounds of a person’s gender, marital status, race, religion, colour, age, disability or sexual orientation. Every candidate will be assessed only in accordance with their merits, qualifications and abilities to perform the duties of the job.

Oxford Nanopore’s goal is to bring the widest benefits to society through enabling the analysis of anything, by anyone, anywhere. The company has developed a new generation of nanopore-based sensing technology enabling the real-time, high-performance, accessible and scalable analysis of DNA and RNA. The technology is used in more than 100 countries to understand the biology of humans and diseases, plants, animals, bacteria, viruses and whole environments.


Oxford Nanopore was founded in 2005 as a spin-out from the University of Oxford and now employs over 1000 employees around the world.

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