Scientist, Biochemistry /Biophysics, Cardiovascular Discovery Biology

Job Description

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Immunology and Cardiovascular Thematic Research Center (TRC) at BMS is one of the fundamental Research and Early Development (R&ED) units delivering therapeutics to patients. Our mission is to create transformative medicines of tomorrow based on the cutting-edge science of today. We leverage BMS’s internal invention of engine that includes industry-leading expertise in small molecule chemistry, protein biotherapeutics, cell therapy, protein degradation, nucleic acids, and other therapeutic modalities. We work closely with our R&ED colleagues in clinical and non-clinical development, project leadership, translational medicine, and informatics to advance therapies based on a deep understanding of causal human biology. Further, we collaborate across the biopharmaceutical ecosystem to establish partnerships that complement our internal expertise.

Here, you’ll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You’ll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

We are seeking an experienced, knowledgeable, and self-motivated scientist to join our Cardiovascular Discovery Biology team to support cardiovascular research and early discovery efforts within the BMS organization. The successful candidate will work collaboratively with drug discovery and translational science teams in a variety of disciplines to explore novel approaches to enable a mechanistic understanding of small molecule modulators, as well as provide laboratory and experimental support for cardiovascular research programs.

The starting compensation for this job is a range from $97,000 to $135,300, plus incentive cash and stock opportunities (based on eligibility). The starting pay takes into account characteristics of the job, such as required skills and where the job is performed. Final, individual compensation is decided based on demonstrated experience. For more on benefits, please visit our BMS Careers site. Eligibility for specific benefits listed in our careers site may vary based on the job and location.

Essential Duties and Job Responsibilities:

Characterize protein targets involved in cardiac diseases as well as determine the molecular mechanism of action of drug candidates.
Develop and implement novel biochemical/biophysical assays to investigate how potential therapeutic agents modulate the targeted protein function.
Characterize small molecule modulators using biochemical and biophysical assays to support Hit-to-lead, Lead-optimization, mechanism of action, and translational efforts.
Conducting scientific research to understand the molecular mechanism of CV disease and define new therapeutic targets.
Present experimental hypotheses plans and results at internal and external meetings.
The scientist will work in a multidisciplinary environment and is expected to collaborate effectively with colleagues across the organization.
Basic Qualifications:

Ph.D. in Biochemistry, Biophysics, Molecular Biology.
Or

Masters with 3+ years of academic/industry experience.
Or

Bachelors with 5+ years of academic/industry experience
Preferred Qualifications:

Broad experience in developing and optimizing biochemical/biophysical assays (e.g.TR-FRET, luminescence, fluorescence polarization, SPR).
Hands-on experience in enzyme kinetics and knowledge of stopped-flow kinetics is preferred.
Hands-on experience of characterizing small molecule modulators using biochemical/biophysical methods is a plus.
Knowledge and experience in sarcomere biology and CV diseases (a strong plus).
Experience with molecular cloning, gene editing is a plus.
Strong problem-solving skills, ability to develop new techniques and methodologies.
Excellent laboratory skills, prioritizing accurate and reproducible work.
Excellent organizational and time management skills.
Must be self-motivated, detail-oriented, collaborative, and able to work effectively in a multidisciplinary discovery team.
Good interpersonal communication and presentation skills are essential.
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to

[email protected]

. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Tagged as: Biochemist